Research and Teaching

Lab Research

One of the special aspects of this practice is our commitment to the advancement of knowledge and improvement in treatment of complex disorders of the gastrointestinal and immune systems. We maintain an active research lab at Buffalo General where we conduct research on the mechanisms of disease. We very frequently have research fellows who work in the lab with us on different projects. Dr. Maya Srivastava has mentored dozens of students, residents, and fellows over the years, and published many scholarly abstracts and journal articles on mucosal immunology.

Fellows Dr. Manisha Relan (Allergy- Immunology) and Dr. Katie Agnello (Gastroenterology) completed our study of Mycoplasma pneumoniae infection in eosinophilic esophagitis patients, and now are Attending physicians in NY and Florida, respectively. Dr. Tara Menon, who led our most recent study on serum soluble MADCAM-1 levels in ulcerative colitis and Crohns disease, has had her work accepted for presentation Fall 2018 at the American College of Gastroenterology, and will start as a new Attending in Gastroenterology in Ohio, 2018.

Dr. Katie Agnello

Dr. Tara Menon

Clinical Research

In addition to lab research, patients in the practice have opportunities to participate in clinical research. Nurse Carol Hammond is in charge of these infusion and registry studies. In the past we were a study site for the use of an anti-IL5 in the treatment of eosinophilic esophagitis, and a registry site for Pediatric Remicade patients. The anti-IL5 (Cinquair) is now FDA approved for asthma.

Community Speaking

Dr. Maya Srivastava is honored to be on the National Faculty Speaker’s Bureau for Abbvie (Humira), Janssen (Remicade, Stelara), and Takeda (Entyvio), and lectures to health care professionals all over the USA on the safe and appropriate use of these medications.

Please contact us at 716-688-0525 if you would like to learn more about our research projects or are interested in participating in the future.

A list of some of our more recent research publications is included below:

1 Srivastava MD. The innate immune system in endometriosis: expression of defensins, toll-like receptors, and signaling pathway MRNA’s by MD-E cell line. Poster Presentation, Society for Gynecologic Investigation (SGI) 2005.
2 Srivastava MD, Srivastava BIS. Expression of natural killer cell cytotoxicity receptors in SRIK-NKL Cell Line. Oral Presentation, AAAAI 2005.
3 Srivastava, MD, Srivastava BIS. Expression of GITR and FOX-P3 by human leukemic cell lines and normal NK, NK-T andCD8+ Lymphocytes. World Congress of Gastroenterology, Montreal, Canada, October 2005.
4 Srivastava MD, Check JH, BIS Srivastava, and Thomas A. Inhibition of progesterone induced blocking factor (PIBF) in human leukemic cell line by mifepristone (RU486). Presented at AACR April 2006.
5 Srivastava MD, Shah P, Blume J, Schwartz S. Efficacy of Infliximab in a Patient with Autoimmune Hepatitis- Primary Biliary Cirrhosis Overlap Syndrome (AIH-PBC). Poster presentation at ACG October 2006.
6 Srivastava MD, Rohilla R , Baig MS, Zaidi SM , Chintanaboina J, Moore M, Qazi KJ, Ambrus J Sr. Effect of Human Alpha Defensin-5 (HAD-5) on Cytokine Expression by CaCo-2 Colonocytes: A Possible Mechanism of THI Predominance in Crohn’s Disease. (late breaking oral presentation AAAAI 2007)Minhaus A, Khan O, Srivastava MD. Top Down versus Step Up Therapy in New Diagnosis Pediatric Crohns Disease. Presented at American College of Gastroenterology 10-2010.
7 Shah A, Moore M, Srivastava MD. Incidence of Acid and Alkaline Reflux in Adult and Pediatric Patients with Eosinophilic Esophagitis. Presented at American College of Gastroenterology 10-2010.
8 Shah A. Moore M, Srivastava MD. Treatment Outcome of Pediatric and Adult Patients with Eosinophilic Esophagitis in the Private Practice Setting. Presented at North American Society of Pediatric Gastroenterology, Hepatology and Nutrition 10-2010.
9 Leykeman O., Srivastava MD. Outcome of Adult Patients with Crohns Disease Under the Care of Pediatric Gastroenterology. Presented (Poster) at North American Society of Pediatric Gastroenterology, Hepatology and Nutrition 10-2011.
10 Hussein A. Srivastava MD. Assessment of Bone Health in Patients with Eosinophilic Esophagitis. Presented (Poster) at the American College of Asthma Allergy and Immunology 11-2011.
11 Srivastava MD, Srivastava B. IL-35 is Present in Human Milk. Accepted for Late Breaking Poster Presentation at the American Academy of Asthma, Allergy and Immunology 3-2012.
12 Taefi A, Srivastava MD. Relevance of Guidelines for Nutritional Screening In Adult Patients with Celiac Disease in the Private Practice Setting. ACG 2012.Srivastava, MD. Role of Mycoplasma pneumoniae in Eosinophilic Esophagitis. ACAAI in San Diego, CA 2013.
13 Srivastava, MD. Role of Mycoplasma pneumoniae in Eosinophilic Esophagitis. ACAAI in San Diego, CA 2013
14 Menon, T, and Srivastava MD. Soluble MADCAM-1: A Potential Predictor Of Clinical Outcome In Inflammatory Bowel Disease (IBD). Accepted for presentation ACG 2018.